Function and Biology Details
Reaction catalysed:
Preferential cleavage: -Asp-|- >> -Asn-|- > -Met-|-, -Ser-|-.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Granzyme B and peptide (preferred)
PDBe Complex ID:
PDB-CPX-145176 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Granzyme B
Molecule details ›
Chain: A
Length: 227 amino acids
Theoretical weight: 25.58 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Length: 227 amino acids
Theoretical weight: 25.58 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P10144 (Residues: 21-247; Coverage: 99%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Ligands and Environments
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 17-ID
Spacegroup:
P212121
Expression systems:
- Spodoptera frugiperda
- Not provided
