› 1ifa

X-ray diffraction
2.6Å resolution

THREE-DIMENSIONAL CRYSTAL STRUCTURE OF RECOMBINANT MURINE INTERFERON-BETA

Released:
DOI: 10.2210/pdb1ifa/pdb
PDB entry 1ifa coloured by chain, front view.
PDB entry 1ifa coloured by chain, side view.
PDB entry 1ifa coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Three-dimensional crystal structure of recombinant murine interferon-beta.
Senda T, Shimazu T, Matsuda S, Kawano G, Shimizu H, Nakamura KT, Mitsui Y
EMBO J 11 3193-201 (1992)
PMID: 1505514

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134398 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interferon beta Chain: A
Molecule details ›
Chain: A
Length: 158 amino acids
Theoretical weight: 19.42 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P01575 (Residues: 24-181; Coverage: 98%)
Gene names: Ifb, Ifnb, Ifnb1
Sequence domains: Interferon alpha/beta domain

Ligands and Environments

1 bound ligand:
Ligand ASN 1 x ASN
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P65
Unit cell:
a: 71.4Å b: 71.4Å c: 79.6Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.205 0.205 not available
Expression system: Not provided

Quick links

Citations

24 review citations

3D domain swapping: a mechanism for oligomer assembly.
Bennett et al. (1995)
23 more