Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Acute myeloid leukemia 1 protein (AML1)/Runt
- Basic-leucine zipper domain
- Core-binding factor, beta subunit superfamily
- Runt domain
- Basic-leucine zipper domain superfamily
- CCAAT/enhancer-binding protein C/EBP
- Core-binding factor, beta subunit
- p53/RUNT-type transcription factor, DNA-binding domain superfamily
1 more domain
Structure domains:
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113976 (preferred)
Entry contents:
3 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (5 distinct):
CCAAT/enhancer-binding protein beta
Molecule details ›
Chains: A, B
Length: 78 amino acids
Theoretical weight: 9.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Basic region leucine zipper
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 78 amino acids
Theoretical weight: 9.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P17676 (Residues: 259-336; Coverage: 23%)
Sequence domains: Basic region leucine zipper
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Runt-related transcription factor 1
Molecule details ›
Chain: C
Length: 123 amino acids
Theoretical weight: 13.72 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Runt domain
Structure domains: Immunoglobulin-like
Length: 123 amino acids
Theoretical weight: 13.72 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q03347 (Residues: 60-182; Coverage: 27%)
Sequence domains: Runt domain
Structure domains: Immunoglobulin-like
Core-binding factor subunit beta
Molecule details ›
Chain: D
Length: 141 amino acids
Theoretical weight: 16.61 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Core binding factor beta subunit
Structure domains: Core binding factor, beta subunit
Length: 141 amino acids
Theoretical weight: 16.61 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q08024 (Residues: 1-141; Coverage: 75%)
Sequence domains: Core binding factor beta subunit
Structure domains: Core binding factor, beta subunit
