› 1ity

Solution NMR

Solution structure of the DNA binding domain of human TRF1

Released:
DOI: 10.2210/pdb1ity/pdb
PDB entry 1ity coloured by chain, ensemble of 25 models, front view.
PDB entry 1ity coloured by chain, ensemble of 25 models, side view.
PDB entry 1ity coloured by chain, ensemble of 25 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of a telomeric DNA complex of human TRF1.
Nishikawa T, Okamura H, Nagadoi A, König P, Rhodes D, Nishimura Y
Structure 9 1237-51 (2001)
PMID: 11738049

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156970 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Telomeric repeat-binding factor 1 Chain: A
Molecule details ›
Chain: A
Length: 69 amino acids
Theoretical weight: 8.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P54274 (Residues: 371-439; Coverage: 16%)
Gene names: PIN2, TERF1, TRBF1, TRF, TRF1
Sequence domains: Myb-like DNA-binding domain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry/simulated annealing
Expression system: Escherichia coli

Quick links

Citations

9 review citations

How shelterin protects mammalian telomeres.
Palm et al. (2008)
8 more

7 mentions without citation

Telomerase and telomere-associated proteins: structural insights into mechanism and evolution.
Lewis et al. (2012)
6 more