› 1iu1

X-ray diffraction
1.8Å resolution

Crystal structure of human gamma1-adaptin ear domain

Released:
DOI: 10.2210/pdb1iu1/pdb
PDB entry 1iu1 coloured by chain, front view.
PDB entry 1iu1 coloured by chain, side view.
PDB entry 1iu1 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for the accessory protein recruitment by the gamma-adaptin ear domain.
Nogi T, Shiba Y, Kawasaki M, Shiba T, Matsugaki N, Igarashi N, Suzuki M, Kato R, Takatsu H, Nakayama K, Wakatsuki S
Nat Struct Biol 9 527-31 (2002)
PMID: 12042876

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129101 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
AP-1 complex subunit gamma-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 146 amino acids
Theoretical weight: 16.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O43747 (Residues: 677-822; Coverage: 18%)
Gene names: ADTG, AP1G1, CLAPG1
Sequence domains: Adaptin C-terminal domain
Structure domains: Immunoglobulin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P43212
Unit cell:
a: 62.132Å b: 62.132Å c: 147.869Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.226 0.248
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Adaptors for clathrin coats: structure and function.
Owen et al. (2004)
6 more

2 mentions without citation

Molecular dynamics study of naturally existing cavity couplings in proteins.
Barbany et al. (2015)
1 more