› 1j0w

X-ray diffraction
2.5Å resolution

Crystal Structure Analysis of the Dok-5 PTB Domain

Released:
DOI: 10.2210/pdb1j0w/pdb
PDB entry 1j0w coloured by chain, front view.
PDB entry 1j0w coloured by chain, side view.
PDB entry 1j0w coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Shi N, Ding Y, Qiang BQ, Yuan JG, Rao ZH

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192810 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Docking protein 5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 103 amino acids
Theoretical weight: 12.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9P104 (Residues: 133-232; Coverage: 33%)
Gene names: C20orf180, DOK5
Sequence domains: PTB domain (IRS-1 type)
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P3221
Unit cell:
a: 75.89Å b: 75.89Å c: 107.96Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.226 0.226 0.27
Expression system: Escherichia coli

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