Function and Biology Details
Reaction catalysed:
GTP + IMP + L-aspartate = GDP + phosphate + N(6)-(1,2-dicarboxyethyl)-AMP
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Adenylosuccinate synthetase
- Adenylosuccinate synthetase, domain 3
- Adenylosuccinate synthase, active site
- Adenylosuccinate synthetase, domain 2
- Adenylosuccinate synthase, GTP-binding site
- Adenylosuccinate synthetase, domain 1
- P-loop containing nucleoside triphosphate hydrolase
- Adenylosuccinate synthetase isozyme 1, chordates
Structure domain:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Adenylosuccinate synthetase isozyme 1 (preferred)
PDBe Complex ID:
PDB-CPX-151258 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL9-2
Spacegroup:
P43212
Expression system: Escherichia coli BL21(DE3)