› 1j7o

Solution NMR

Solution structure of Calcium-calmodulin N-terminal domain

Released:
DOI: 10.2210/pdb1j7o/pdb
PDB entry 1j7o coloured by chain, ensemble of 3 models, front view.
PDB entry 1j7o coloured by chain, ensemble of 3 models, side view.
PDB entry 1j7o coloured by chain, ensemble of 3 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of Ca(2+)-calmodulin reveals flexible hand-like properties of its domains.
Chou JJ, Li S, Klee CB, Bax A
Nat Struct Biol 8 990-7 (2001)
PMID: 11685248

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143908 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calmodulin-1 Chain: A
Molecule details ›
Chain: A
Length: 76 amino acids
Theoretical weight: 8.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP23 (Residues: 2-77; Coverage: 51%)
Gene names: CALM, CALM1, CAM, CAM1
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

22 review citations

Weak alignment offers new NMR opportunities to study protein structure and dynamics.
Bax A. (2003)
21 more

12 mentions without citation

A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction.
Gsponer et al. (2008)
11 more