Function and Biology Details
Reactions catalysed:
Indan-1-ol + NAD(P)(+) = indanone + NAD(P)H
Androsterone + NAD(P)(+) = 5-alpha-androstane-3,17-dione + NAD(P)H
A 3-alpha-hydroxysteroid + NAD(P)(+) = a 3-oxosteroid + NAD(P)H
Androstan-3-alpha,17-beta-diol + NAD(+) = 17-beta-hydroxyandrostan-3-one + NADH
17-beta-estradiol + NAD(P)(+) = estrone + NAD(P)H
Trans-1,2-dihydrobenzene-1,2-diol + NADP(+) = catechol + NADPH
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Aldo-keto reductase family 1 member C2 (preferred)
PDBe Complex ID:
PDB-CPX-156658 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aldo-keto reductase family 1 member C2
Molecule details ›
Chains: A, B
Length: 323 amino acids
Theoretical weight: 36.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Aldo/keto reductase family
Structure domains: NADP-dependent oxidoreductase domain
Length: 323 amino acids
Theoretical weight: 36.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P52895 (Residues: 2-323; Coverage: 100%)
Sequence domains: Aldo/keto reductase family
Structure domains: NADP-dependent oxidoreductase domain
