1je4

Solution NMR

Solution structure of the monomeric variant of the chemokine MIP-1beta

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146517 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-C motif chemokine 4 Chain: A
Molecule details ›
Chain: A
Length: 69 amino acids
Theoretical weight: 7.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P13236 (Residues: 24-92; Coverage: 100%)
Gene names: CCL4, LAG1, MIP1B, SCYA4
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: The initial fold was obtained by distance geometry and further refined by simulated annealing.
Expression system: Escherichia coli BL21(DE3)