› 1jjr

Solution NMR

The Three-Dimensional Structure of the C-terminal DNA Binding Domain of Human Ku70

Released:
DOI: 10.2210/pdb1jjr/pdb
PDB entry 1jjr coloured by chain, ensemble of 20 models, front view.
PDB entry 1jjr coloured by chain, ensemble of 20 models, side view.
PDB entry 1jjr coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The three-dimensional structure of the C-terminal DNA-binding domain of human Ku70.
Zhang Z, Zhu L, Lin D, Chen F, Chen DJ, Chen Y
J Biol Chem 276 38231-6 (2001)
PMID: 11457852

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146400 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
X-ray repair cross-complementing protein 6 Chain: A
Molecule details ›
Chain: A
Length: 151 amino acids
Theoretical weight: 16.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12956 (Residues: 535-609; Coverage: 12%)
Gene names: G22P1, XRCC6
Sequence domains: SAP domain
Structure domains: SAP domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

9 review citations

A means to a DNA end: the many roles of Ku.
Downs et al. (2004)
8 more

11 mentions without citation

Repair of double-strand breaks by end joining.
Chiruvella et al. (2013)
10 more