› 1jxm

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF THE GMP BOUND SH3-HOOK-GK FRAGMENT OF PSD-95

Released:
DOI: 10.2210/pdb1jxm/pdb
PDB entry 1jxm coloured by chain, front view.
PDB entry 1jxm coloured by chain, side view.
PDB entry 1jxm coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Structural characterization of the intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95.
Tavares GA, Panepucci EH, Brunger AT
Mol Cell 8 1313-25 (2001)
PMID: 11779506

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151877 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Disks large homolog 4 Chain: A
Molecule details ›
Chain: A
Length: 301 amino acids
Theoretical weight: 34.81 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P31016 (Residues: 430-724; Coverage: 41%)
Gene names: Dlg4, Dlgh4, Psd95
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand 5GP 1 x 5GP
Ligand GAI 2 x GAI
Ligand MPD 2 x MPD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1, SSRL BEAMLINE BL9-2
Spacegroup: P41212
Unit cell:
a: 59.724Å b: 59.724Å c: 209.956Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.237 0.26
Expression system: Escherichia coli

Quick links

Citations

22 review citations

PDZ domain proteins of synapses.
Kim et al. (2004)
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10 mentions without citation

Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard.
Terwilliger et al. (2009)
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