› 1k1z

Solution NMR

Solution structure of N-terminal SH3 domain mutant(P33G) of murine Vav

Released:
DOI: 10.2210/pdb1k1z/pdb
PDB entry 1k1z coloured by chain, front view.
PDB entry 1k1z coloured by chain, side view.
PDB entry 1k1z coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Solution structure of N-terminal SH3 domain of Vav and the recognition site for Grb2 C-terminal SH3 domain.
Ogura K, Nagata K, Horiuchi M, Ebisui E, Hasuda T, Yuzawa S, Nishida M, Hatanaka H, Inagaki F
J Biomol NMR 22 37-46 (2002)
PMID: 11885979

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151089 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proto-oncogene vav Chain: A
Molecule details ›
Chain: A
Length: 78 amino acids
Theoretical weight: 8.99 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P27870 (Residues: 583-660; Coverage: 9%)
Gene names: Vav, Vav1
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Vav1: a key signal transducer downstream of the TCR.
Tybulewicz et al. (2003)
2 more

1 mention without citation

Lysine Acetylation Reshapes the Downstream Signaling Landscape of Vav1 in Lymphocytes.
Rodríguez-Fdez et al. (2020)