› 1k5r

Solution NMR

YAP65 WW domain S24-Amino-Ethylsulfanyl-Acetic Acid mutant

Released:
DOI: 10.2210/pdb1k5r/pdb
PDB entry 1k5r coloured by chain, ensemble of 10 models, front view.
PDB entry 1k5r coloured by chain, ensemble of 10 models, side view.
PDB entry 1k5r coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Using flexible loop mimetics to extend phi-value analysis to secondary structure interactions.
Ferguson N, Pires JR, Toepert F, Johnson CM, Pan YP, Volkmer-Engert R, Schneider-Mergener J, Daggett V, Oschkinat H, Fersht A
Proc Natl Acad Sci U S A 98 13008-13 (2001)
PMID: 11687614

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155556 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transcriptional coactivator YAP1 Chain: A
Molecule details ›
Chain: A
Length: 41 amino acids
Theoretical weight: 4.71 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P46937 (Residues: 165-204; Coverage: 8%)
Gene names: YAP1, YAP65
Sequence domains: WW domain
WW domain-binding protein 1 Chain: B
Molecule details ›
Chain: B
Length: 10 amino acids
Theoretical weight: 985 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q96G27 (Residues: 135-143; Coverage: 3%)
Gene name: WBP1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated anneling
Expression system: Not provided

Quick links

Citations

6 review citations

The protein folding 'speed limit'.
Kubelka et al. (2004)
5 more

1 mention without citation

Using flexible loop mimetics to extend phi-value analysis to secondary structure interactions.
Ferguson et al. (2001)