› 1k95

X-ray diffraction
1.9Å resolution

Crystal structure of des(1-52)grancalcin with bound calcium

Released:
DOI: 10.2210/pdb1k95/pdb
PDB entry 1k95 coloured by chain, front view.
PDB entry 1k95 coloured by chain, side view.
PDB entry 1k95 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of Ca(2+)-loaded human grancalcin.
Jia J, Borregaard N, Lollike K, Cygler M
Acta Crystallogr D Biol Crystallogr 57 1843-9 (2001)
PMID: 11717497

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-151259 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Grancalcin Chain: A
Molecule details ›
Chain: A
Length: 165 amino acids
Theoretical weight: 18.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P28676 (Residues: 53-217; Coverage: 76%)
Gene names: GCA, GCL
Sequence domains: EF hand
Structure domains: EF-hand

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X8C
Spacegroup: P6522
Unit cell:
a: 57.65Å b: 57.65Å c: 154.62Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.211 0.211 0.259
Expression system: Escherichia coli

Quick links

Citations

6 citation in other articles

Structural basis for Ca2+ -dependent formation of ALG-2/Alix peptide complex: Ca2+/EF3-driven arginine switch mechanism.
Suzuki et al. (2008)
5 more

2 mentions without citation

Two structural motifs within canonical EF-hand calcium-binding domains identify five different classes of calcium buffers and sensors.
Denessiouk et al. (2014)
1 more