› 1kbn

X-ray diffraction
2Å resolution

Glutathione transferase mutant

Released:
DOI: 10.2210/pdb1kbn/pdb
PDB entry 1kbn coloured by chain, front view.
PDB entry 1kbn coloured by chain, side view.
PDB entry 1kbn coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Rossjohn J, Parker MW

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140593 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase P Chains: A, B
Molecule details ›
Chains: A, B
Length: 209 amino acids
Theoretical weight: 23.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09211 (Residues: 2-210; Coverage: 100%)
Gene names: FAEES3, GST3, GSTP1
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand GSH 2 x GSH
2 bound ligands:
Ligand MES 2 x MES
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 68.873Å b: 78.775Å c: 89.419Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.226 0.244
Expression system: Escherichia coli

Quick links