Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Somatotropin and Growth hormone-binding protein (preferred)
PDBe Complex ID:
PDB-CPX-134129 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Somatotropin
Molecule details ›
Chains: A, D
Length: 191 amino acids
Theoretical weight: 21.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Somatotropin hormone family
Structure domains: Growth Hormone; Chain: A;
Length: 191 amino acids
Theoretical weight: 21.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P01241 (Residues: 27-217; Coverage: 100%)
Sequence domains: Somatotropin hormone family
Structure domains: Growth Hormone; Chain: A;
Growth hormone-binding protein
Molecule details ›
Chains: B, C, E, F
Length: 238 amino acids
Theoretical weight: 27.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: Immunoglobulins
Length: 238 amino acids
Theoretical weight: 27.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P10912 (Residues: 19-256; Coverage: 38%)
Sequence domains:
Structure domains: Immunoglobulins
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL7-1
Spacegroup:
P21
Expression system: Escherichia coli
