› 1kjw

X-ray diffraction
1.8Å resolution

SH3-Guanylate Kinase Module from PSD-95

Released:
DOI: 10.2210/pdb1kjw/pdb
PDB entry 1kjw coloured by chain, front view.
PDB entry 1kjw coloured by chain, side view.
PDB entry 1kjw coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Structure of the SH3-guanylate kinase module from PSD-95 suggests a mechanism for regulated assembly of MAGUK scaffolding proteins.
McGee AW, Dakoji SR, Olsen O, Bredt DS, Lim WA, Prehoda KE
Mol Cell 8 1291-301 (2001)
PMID: 11779504

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151877 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Disks large homolog 4 Chain: A
Molecule details ›
Chain: A
Length: 295 amino acids
Theoretical weight: 34.24 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P31016 (Residues: 430-724; Coverage: 41%)
Gene names: Dlg4, Dlgh4, Psd95
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P41212
Unit cell:
a: 60.509Å b: 60.509Å c: 209.956Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.23 0.25
Expression system: Escherichia coli

Quick links

Citations

45 review citations

PDZ domain proteins of synapses.
Kim et al. (2004)
44 more

12 mentions without citation

Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules.
Zhu et al. (2011)
11 more