› 1kld

Solution NMR

SOLUTION STRUCTURE OF TGF-B1, NMR, MODELS 18-33 OF 33 STRUCTURES

Released:
DOI: 10.2210/pdb1kld/pdb
PDB entry 1kld coloured by chain, ensemble of 16 models, front view.
PDB entry 1kld coloured by chain, ensemble of 16 models, side view.
PDB entry 1kld coloured by chain, ensemble of 16 models, top view.
Source organism: Homo sapiens
Primary publication:
Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Hinck AP, Archer SJ, Qian SW, Roberts AB, Sporn MB, Weatherbee JA, Tsang ML, Lucas R, Zhang BL, Wenker J, Torchia DA
Biochemistry 35 8517-34 (1996)
PMID: 8679613

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134058 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transforming growth factor beta-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 112 amino acids
Theoretical weight: 12.81 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P01137 (Residues: 279-390; Coverage: 31%)
Gene names: TGFB, TGFB1
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Cricetulus griseus

Quick links

Citations

27 review citations

TGF-beta signal transduction.
Massagué J. (1998)
26 more

4 mentions without citation

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Quan et al. (2021)
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