› 1knt

X-ray diffraction
1.6Å resolution

THE 1.6 ANGSTROMS STRUCTURE OF THE KUNITZ-TYPE DOMAIN FROM THE ALPHA3 CHAIN OF THE HUMAN TYPE VI COLLAGEN

Released:
DOI: 10.2210/pdb1knt/pdb
PDB entry 1knt coloured by chain, front view.
PDB entry 1knt coloured by chain, side view.
PDB entry 1knt coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The 1.6 A structure of Kunitz-type domain from the alpha 3 chain of human type VI collagen.
Arnoux B, Mérigeau K, Saludjian P, Norris F, Norris K, Bjørn S, Olsen O, Petersen L, Ducruix A
J Mol Biol 246 609-17 (1995)
PMID: 7533217

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146098 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Collagen alpha-3(VI) chain Chain: A
Molecule details ›
Chain: A
Length: 58 amino acids
Theoretical weight: 6.64 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P12111 (Residues: 3108-3165; Coverage: 2%)
Gene name: COL6A3
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
Structure domains: Pancreatic trypsin inhibitor Kunitz domain

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 25.7Å b: 38.2Å c: 28.8Å
α: 90° β: 109° γ: 90°
R-values:
R R work R free
0.189 0.189 not available
Expression system: Saccharomyces cerevisiae

Quick links

Citations

16 citation in other articles

Interscaffolding additivity: binding of P1 variants of bovine pancreatic trypsin inhibitor to four serine proteases.
Krowarsch et al. (1999)
15 more

2 mentions without citation

Thoroughly sampling sequence space: large-scale protein design of structural ensembles.
Larson et al. (2002)
1 more