Function and Biology Details
Reaction catalysed:
Preferential cleavage: Lys-|-Xaa > Arg-|-Xaa, higher selectivity than trypsin. Converts fibrin into soluble products.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assemblies composition:
Assembly name:
Streptokinase C and Angiostatin (preferred)
PDBe Complex ID:
PDB-CPX-133231 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Plasmin light chain B
Molecule details ›
Chain: A
Length: 248 amino acids
Theoretical weight: 27.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Length: 248 amino acids
Theoretical weight: 27.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P00747 (Residues: 563-810; Coverage: 31%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Streptokinase C
Molecule details ›
Chain: B
Length: 136 amino acids
Theoretical weight: 14.91 KDa
Source organism: Streptococcus dysgalactiae subsp. equisimilis
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: Staphylokinase/Streptokinase family
Structure domains: Ubiquitin-like (UB roll)
Length: 136 amino acids
Theoretical weight: 14.91 KDa
Source organism: Streptococcus dysgalactiae subsp. equisimilis
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P00779 (Residues: 27-173; Coverage: 33%)
Sequence domains: Staphylokinase/Streptokinase family
Structure domains: Ubiquitin-like (UB roll)
