› 1l5t

X-ray diffraction
3Å resolution

Crystal Structure of a Domain-Opened Mutant (R121D) of the Human Lactoferrin N-lobe Refined From a Merohedrally-Twinned Crystal Form.

Released:
DOI: 10.2210/pdb1l5t/pdb
PDB entry 1l5t coloured by chain, front view.
PDB entry 1l5t coloured by chain, side view.
PDB entry 1l5t coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of a domain-opened mutant (R121D) of the human lactoferrin N-lobe refined from a merohedrally twinned crystal form.
Jameson GB, Anderson BF, Breyer WA, Day CL, Tweedie JW, Baker EN
Acta Crystallogr D Biol Crystallogr 58 955-62 (2002)
PMID: 12037297

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136228 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lactotransferrin Chains: A, B
Molecule details ›
Chains: A, B
Length: 332 amino acids
Theoretical weight: 36.92 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P02788 (Residues: 21-351; Coverage: 48%)
Gene names: GIG12, LF, LTF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P31
Unit cell:
a: 151.3Å b: 151.3Å c: 48.6Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.141 0.139 0.199
Expression system: Cricetulus griseus

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Citations

3 citation in other articles

Crystal structure of a proteolytically generated functional monoferric C-lobe of bovine lactoferrin at 1.9A resolution.
Sharma et al. (2003)
2 more