› 1lcf

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF COPPER-AND OXALATE-SUBSTITUTED HUMAN LACTOFERRIN AT 2.0 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb1lcf/pdb
PDB entry 1lcf coloured by chain, front view.
PDB entry 1lcf coloured by chain, side view.
PDB entry 1lcf coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of copper- and oxalate-substituted human lactoferrin at 2.0 A resolution.
Smith CA, Anderson BF, Baker HM, Baker EN
Acta Crystallogr D Biol Crystallogr 50 302-16 (1994)
PMID: 15299444

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lactotransferrin Chain: A
Molecule details ›
Chain: A
Length: 691 amino acids
Theoretical weight: 76.22 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P02788 (Residues: 20-710; Coverage: 100%)
Gene names: GIG12, LF, LTF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

4 bound ligands:
Ligand NAG 1 x NAG
Ligand CU 2 x CU
Ligand CO3 1 x CO3
Ligand OXL 1 x OXL
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 155.8Å b: 97.1Å c: 56.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 not available not available
Expression system: Not provided

Quick links

Citations

1 review citation

The nonheme iron in photosystem II.
Müh et al. (2013)
5 other articles

5 mentions without citation

Structure of the two transmembrane Cu+ transport sites of the Cu+ -ATPases.
González-Guerrero et al. (2008)
4 more