› 1lct

X-ray diffraction
2Å resolution

STRUCTURE OF THE RECOMBINANT N-TERMINAL LOBE OF HUMAN LACTOFERRIN AT 2.0 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb1lct/pdb
PDB entry 1lct coloured by chain, front view.
PDB entry 1lct coloured by chain, side view.
PDB entry 1lct coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the recombinant N-terminal lobe of human lactoferrin at 2.0 A resolution.
Day CL, Anderson BF, Tweedie JW, Baker EN
J Mol Biol 232 1084-100 (1993)
PMID: 8371268

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136228 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lactotransferrin Chain: A
Molecule details ›
Chain: A
Length: 333 amino acids
Theoretical weight: 37.08 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P02788 (Residues: 21-352; Coverage: 48%)
Gene names: GIG12, LF, LTF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

2 bound ligands:
Ligand FE 1 x FE
Ligand CO3 1 x CO3
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 133Å b: 58.3Å c: 58.3Å
α: 90° β: 114.7° γ: 90°
R-values:
R R work R free
0.184 not available not available
Expression system: Not provided

Quick links

Citations

4 review citations

Structural trees for protein superfamilies.
Efimov AV. (1997)
3 more

1 mention without citation

Bioinformatics perspective on rhomboid intramembrane protease evolution and function.
Kinch et al. (2013)