1lq8

X-ray diffraction
2.4Å resolution

Crystal structure of cleaved protein C inhibitor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-138559 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (5 distinct):
Plasma serine protease inhibitor Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 346 amino acids
Theoretical weight: 38.65 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P05154 (Residues: 30-375; Coverage: 89%)
Gene names: PCI, PLANH3, PROCI, SERPINA5
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:
Plasma serine protease inhibitor Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 31 amino acids
Theoretical weight: 3.74 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P05154 (Residues: 376-406; Coverage: 8%)
Gene names: PCI, PLANH3, PROCI, SERPINA5

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, NDG
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: MAN
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 55.2Å b: 244.03Å c: 66.4Å
α: 90° β: 91.98° γ: 90°
R-values:
R R work R free
0.222 0.222 0.279