› 1lve

X-ray diffraction
1.95Å resolution

STRUCTURE OF THE VARIABLE DOMAIN OF HUMAN IMMUNOGLOBULIN K-4 LIGHT CHAIN LEN

Released:
DOI: 10.2210/pdb1lve/pdb
PDB entry 1lve coloured by chain, front view.
PDB entry 1lve coloured by chain, side view.
PDB entry 1lve coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Variable domain structure of kappaIV human light chain Len: high homology to the murine light chain McPC603.
Huang DB, Chang CH, Ainsworth C, Johnson G, Solomon A, Stevens FJ, Schiffer M
Mol Immunol 34 1291-301 (1997)
PMID: 9683271

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138999 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Immunoglobulin kappa variable 4-1 Chain: A
Molecule details ›
Chain: A
Length: 122 amino acids
Theoretical weight: 13.42 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P06312 (Residues: 21-121; Coverage: 100%)
Gene name: IGKV4-1
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2221
Unit cell:
a: 43.11Å b: 83.53Å c: 54.47Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.16 0.15 0.27
Expression system: Not provided

Quick links

Citations

1 review citation

Crystal structures of human antibodies: a detailed and unfinished tapestry of immunoglobulin gene products.
Ramsland et al. (2002)
19 other articles

12 mentions without citation

Backrub-like backbone simulation recapitulates natural protein conformational variability and improves mutant side-chain prediction.
Smith et al. (2008)
11 more