› 1lz6

X-ray diffraction
1.8Å resolution

STRUCTURAL AND FUNCTIONAL ANALYSES OF THE ARG-GLY-ASP SEQUENCE INTRODUCED INTO HUMAN LYSOZYME

Released:
DOI: 10.2210/pdb1lz6/pdb
PDB entry 1lz6 coloured by chain, front view.
PDB entry 1lz6 coloured by chain, side view.
PDB entry 1lz6 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural and functional analyses of the Arg-Gly-Asp sequence introduced into human lysozyme.
Yamada T, Matsushima M, Inaka K, Ohkubo T, Uyeda A, Maeda T, Titani K, Sekiguchi K, Kikuchi M
J Biol Chem 268 10588-92 (1993)
PMID: 8486712

Function and Biology Details

Reaction catalysed: 
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158303 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysozyme C Chain: A
Molecule details ›
Chain: A
Length: 138 amino acids
Theoretical weight: 15.46 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P61626 (Residues: 19-92, 93-148; Coverage: 100%)
Gene names: LYZ, LZM
Sequence domains: C-type lysozyme/alpha-lactalbumin family
Structure domains: Lysozyme

Ligands and Environments

1 bound ligand:
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 56.79Å b: 60.97Å c: 33.66Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.152 not available not available
Expression system: Not provided

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Citations

7 review citations

Platelet glycoprotein IIb/IIIa receptors in cardiovascular medicine.
Lefkovits et al. (1995)
6 more