› 1m7t

Solution NMR

Solution Structure and Dynamics of the Human-Escherichia coli Thioredoxin Chimera: Insights into Thermodynamic Stability

Released:
DOI: 10.2210/pdb1m7t/pdb
PDB entry 1m7t coloured by chain, ensemble of 21 models, front view.
PDB entry 1m7t coloured by chain, ensemble of 21 models, side view.
PDB entry 1m7t coloured by chain, ensemble of 21 models, top view.
Source organisms:
Primary publication:
Solution structure and dynamics of the human-Escherichia coli thioredoxin chimera: insights into thermodynamic stability.
Dangi B, Dobrodumov AV, Louis JM, Gronenborn AM
Biochemistry 41 9376-88 (2002)
PMID: 12135359

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141953 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin; Thioredoxin 1 Chain: A
Molecule details ›
Chain: A
Length: 107 amino acids
Theoretical weight: 11.69 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P10599 (Residues: 1-66; Coverage: 63%)
  • Canonical: P0AA25 (Residues: 69-108; Coverage: 37%)
Gene names: JW5856, TRDX, TRX, TRX1, TXN, b3781, fipA, trxA, tsnC
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: see publication
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 citation in other articles

Model-free analysis of protein dynamics: assessment of accuracy and model selection protocols based on molecular dynamics simulation.
Chen et al. (2004)
2 more

4 mentions without citation

Identification of novel interaction between ADAM17 (a disintegrin and metalloprotease 17) and thioredoxin-1.
Aragão et al. (2012)
3 more