› 1m8a

X-ray diffraction
1.7Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160285 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-C motif chemokine 20 Chains: A, B
Molecule details ›
Chains: A, B
Length: 70 amino acids
Theoretical weight: 8.04 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P78556 (Residues: 27-96; Coverage: 100%)
Gene names: CCL20, LARC, MIP3A, SCYA20
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

1 bound ligand:
Ligand IPA 10 x IPA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: P61
Unit cell:
a: 70.822Å b: 70.822Å c: 71.768Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.193 0.19 0.238
Expression system: Not provided

Quick links

Citations

39 review citations

IL-17 and Th17 Cells.
Korn et al. (2009)
38 more

10 mentions without citation

The marriage of chemokines and galectins as functional heterodimers.
von Hundelshausen et al. (2021)
9 more