› 1mil

X-ray diffraction
2.7Å resolution

TRANSFORMING PROTEIN

Released:
DOI: 10.2210/pdb1mil/pdb
PDB entry 1mil coloured by chain, front view.
PDB entry 1mil coloured by chain, side view.
PDB entry 1mil coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the SH2 domain from the adaptor protein SHC: a model for peptide binding based on X-ray and NMR data.
Mikol V, Baumann G, Zurini MG, Hommel U
J Mol Biol 254 86-95 (1995)
PMID: 7473762

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151418 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SHC-transforming protein 1 Chain: A
Molecule details ›
Chain: A
Length: 104 amino acids
Theoretical weight: 11.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P29353 (Residues: 482-583; Coverage: 18%)
Gene names: SHC, SHC1, SHCA
Sequence domains: SH2 domain
Structure domains: SH2 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 26.37Å b: 41.55Å c: 97.54Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.173 not available
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Signaling via Shc family adapter proteins.
Ravichandran KS. (2001)
7 other articles

5 mentions without citation

PROMALS3D web server for accurate multiple protein sequence and structure alignments.
Pei et al. (2008)
4 more