› 1mjd

Solution NMR

Structure of N-terminal domain of human doublecortin

Released:
DOI: 10.2210/pdb1mjd/pdb
PDB entry 1mjd coloured by chain, ensemble of 20 models, front view.
PDB entry 1mjd coloured by chain, ensemble of 20 models, side view.
PDB entry 1mjd coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The DCX-domain tandems of doublecortin and doublecortin-like kinase.
Kim MH, Cierpicki T, Derewenda U, Krowarsch D, Feng Y, Devedjiev Y, Dauter Z, Walsh CA, Otlewski J, Bushweller JH, Derewenda ZS
Nat Struct Biol 10 324-33 (2003)
PMID: 12692530

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129017 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neuronal migration protein doublecortin Chain: A
Molecule details ›
Chain: A
Length: 113 amino acids
Theoretical weight: 12.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O43602 (Residues: 45-150; Coverage: 29%)
Gene names: DBCN, DCX, LISX
Sequence domains: Doublecortin
Structure domains: Doublecortin domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: automatic NOESY cross-peaks assignment, torsion angle dynamics, simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

15 review citations

Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases.
Bogoyevitch et al. (2006)
14 more

9 mentions without citation

The natural history of ubiquitin and ubiquitin-related domains.
Burroughs et al. (2012)
8 more