› 1mlb

X-ray diffraction
2.1Å resolution

MONOCLONAL ANTIBODY FAB D44.1 RAISED AGAINST CHICKEN EGG-WHITE LYSOZYME

Released:
DOI: 10.2210/pdb1mlb/pdb
PDB entry 1mlb coloured by chain, front view.
PDB entry 1mlb coloured by chain, side view.
PDB entry 1mlb coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1.
Braden BC, Souchon H, Eiselé JL, Bentley GA, Bhat TN, Navaza J, Poljak RJ
J Mol Biol 243 767-81 (1994)
PMID: 7966295

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-208557 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Immunoglobulin kappa constant Chain: A
Molecule details ›
Chain: A
Length: 214 amino acids
Theoretical weight: 23.61 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P01837 (Residues: 1-107; Coverage: 100%)
Gene name: Igkc
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
IGG1-KAPPA D44.1 FAB (HEAVY CHAIN) Chain: B
Molecule details ›
Chain: B
Length: 218 amino acids
Theoretical weight: 23.22 KDa
Source organism: Mus musculus
Expression system: Not provided
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 79.7Å b: 136.2Å c: 43Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 not available 0.274
Expression system: Not provided

Quick links

Citations

12 review citations

Interactions of protein antigens with antibodies.
Davies et al. (1996)
11 more

29 mentions without citation

A new clustering of antibody CDR loop conformations.
North et al. (2011)
28 more