› 1mx8

Solution NMR

Two homologous rat cellular retinol-binding proteins differ in local structure and flexibility

Released:
DOI: 10.2210/pdb1mx8/pdb
PDB entry 1mx8 coloured by chain, ensemble of 25 models, front view.
PDB entry 1mx8 coloured by chain, ensemble of 25 models, side view.
PDB entry 1mx8 coloured by chain, ensemble of 25 models, top view.
Source organism: Rattus norvegicus
Primary publication:
Two homologous rat cellular retinol-binding proteins differ in local conformational flexibility.
Lu J, Cistola DP, Li E
J Mol Biol 330 799-812 (2003)
PMID: 12850148

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136052 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Retinol-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 15.72 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P02696 (Residues: 2-135; Coverage: 99%)
Gene names: Rbp-1, Rbp1
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand RTL 1 x RTL
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry simulated annealing
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Cellular retinoid binding-proteins, CRBP, CRABP, FABP5: Effects on retinoid metabolism, function and related diseases.
Napoli JL. (2017)
3 more