Function and Biology Details
Reaction catalysed:
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Pancreatic triacylglycerol lipase and Colipase (preferred)
PDBe Complex ID:
PDB-CPX-136085 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Pancreatic triacylglycerol lipase
Molecule details ›
Chain: A
Length: 449 amino acids
Theoretical weight: 49.57 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Structure domains:
Length: 449 amino acids
Theoretical weight: 49.57 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P16233 (Residues: 17-465; Coverage: 100%)
Sequence domains:
Structure domains:
Colipase
Molecule details ›
Chain: C
Length: 95 amino acids
Theoretical weight: 10.35 KDa
Source organism: Sus scrofa
UniProt:
Sequence domains:
Structure domains: Lipase, subunit A
Length: 95 amino acids
Theoretical weight: 10.35 KDa
Source organism: Sus scrofa
UniProt:
- Canonical: P02703 (Residues: 18-110; Coverage: 98%)
Sequence domains:
Structure domains: Lipase, subunit A
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
LURE BEAMLINE DW32
Spacegroup:
P3221
