› 1nkr

X-ray diffraction
1.7Å resolution

INHIBITORY RECEPTOR (P58-CL42) FOR HUMAN NATURAL KILLER CELLS

Released:
DOI: 10.2210/pdb1nkr/pdb
PDB entry 1nkr coloured by chain, front view.
PDB entry 1nkr coloured by chain, side view.
PDB entry 1nkr coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the inhibitory receptor for human natural killer cells resembles haematopoietic receptors.
Fan QR, Mosyak L, Winter CC, Wagtmann N, Long EO, Wiley DC
Nature 389 96-100 (1997)
PMID: 9288975

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155111 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Killer cell immunoglobulin-like receptor 2DL1 Chain: A
Molecule details ›
Chain: A
Length: 201 amino acids
Theoretical weight: 22.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P43626 (Residues: 22-221; Coverage: 61%)
Gene names: CD158A, KIR2DL1, NKAT1
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P61
Unit cell:
a: 92.36Å b: 92.36Å c: 46.77Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.205 0.227 0.255
Expression system: Escherichia coli

Quick links

Citations

25 review citations

KIR: diverse, rapidly evolving receptors of innate and adaptive immunity.
Vilches et al. (2002)
24 more

20 mentions without citation

Structural basis for recognition of MHC and MHC-like ligands by natural killer cell receptors.
Deng et al. (2006)
19 more