› 1nkx

X-ray diffraction
1.9Å resolution

CRYSTAL STRUCTURE OF A PROTEOLYTICALLY GENERATED FUNCTIONAL MONOFERRIC C-LOBE OF BOVINE LACTOFERRIN AT 1.9A RESOLUTION

Released:
DOI: 10.2210/pdb1nkx/pdb
PDB entry 1nkx coloured by chain, front view.
PDB entry 1nkx coloured by chain, side view.
PDB entry 1nkx coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Crystal structure of a proteolytically generated functional monoferric C-lobe of bovine lactoferrin at 1.9A resolution.
Sharma S, Jasti J, Kumar J, Mohanty AK, Singh TP
J Mol Biol 331 485-96 (2003)
PMID: 12888354

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150260 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Lactotransferrin Chain: A
Molecule details ›
Chain: A
Length: 348 amino acids
Theoretical weight: 38.03 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P24627 (Residues: 361-708; Coverage: 51%)
Gene name: LTF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
4 bound ligands:
Ligand NAG 1 x NAG
Ligand FE 1 x FE
Ligand ZN 2 x ZN
Ligand CO3 1 x CO3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21
Unit cell:
a: 63.359Å b: 50.471Å c: 65.934Å
α: 90° β: 107.72° γ: 90°
R-values:
R R work R free
0.202 0.192 0.222

Quick links

Citations

2 review citations

The nonheme iron in photosystem II.
Müh et al. (2013)
1 more

2 mentions without citation

C-lobe of lactoferrin: the whole story of the half-molecule.
Sharma et al. (2013)
1 more