› 1nwv

Solution NMR

SOLUTION STRUCTURE OF A FUNCTIONALLY ACTIVE COMPONENT OF DECAY ACCELERATING FACTOR

Released:
DOI: 10.2210/pdb1nwv/pdb
PDB entry 1nwv coloured by chain, ensemble of 42 models, front view.
PDB entry 1nwv coloured by chain, ensemble of 42 models, side view.
PDB entry 1nwv coloured by chain, ensemble of 42 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of a functionally active fragment of decay-accelerating factor.
Uhrinova S, Lin F, Ball G, Bromek K, Uhrin D, Medof ME, Barlow PN
Proc Natl Acad Sci U S A 100 4718-23 (2003)
PMID: 12672958

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139968 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Complement decay-accelerating factor Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.35 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P08174 (Residues: 96-222; Coverage: 37%)
Gene names: CD55, CR, DAF
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics
Expression system: Komagataella pastoris

Quick links

Citations

2 review citations

Deciphering complement mechanisms: the contributions of structural biology.
Arlaud et al. (2007)
1 more

4 mentions without citation

Mechanical strength of 17,134 model proteins and cysteine slipknots.
Sikora et al. (2009)
3 more