Function and Biology Details
Biochemical function:
- not assigned
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139026 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Retinoblastoma-associated protein
Molecule details ›
Chains: A, C, E, G
Length: 218 amino acids
Theoretical weight: 25.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Retinoblastoma-associated protein A domain
Structure domains: Cyclin-like
Length: 218 amino acids
Theoretical weight: 25.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P06400 (Residues: 372-589; Coverage: 24%)
Sequence domains: Retinoblastoma-associated protein A domain
Structure domains: Cyclin-like
Retinoblastoma-associated protein
Molecule details ›
Chains: B, D, F, H
Length: 152 amino acids
Theoretical weight: 18.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Retinoblastoma-associated protein B domain
Structure domains: Cyclin-like
Length: 152 amino acids
Theoretical weight: 18.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P06400 (Residues: 636-787; Coverage: 16%)
Sequence domains: Retinoblastoma-associated protein B domain
Structure domains: Cyclin-like
Transcription factor E2F1
Molecule details ›
Chains: P, Q, R, S
Length: 18 amino acids
Theoretical weight: 2.13 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 18 amino acids
Theoretical weight: 2.13 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: Q01094 (Residues: 409-426; Coverage: 4%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID13
Spacegroup:
C2
Expression systems:
- Escherichia coli
- Not provided
