Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Vitronectin-PAI-1 complex (preferred)
PDBe Complex ID:
PDB-CPX-137318 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Plasminogen activator inhibitor 1
Molecule details ›
Chain: A
Length: 379 amino acids
Theoretical weight: 42.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:
Length: 379 amino acids
Theoretical weight: 42.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P05121 (Residues: 24-402; Coverage: 100%)
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:
Somatomedin-B
Molecule details ›
Chain: B
Length: 51 amino acids
Theoretical weight: 5.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Somatomedin B domain
Length: 51 amino acids
Theoretical weight: 5.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P04004 (Residues: 20-70; Coverage: 11%)
Sequence domains: Somatomedin B domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 19-ID
Spacegroup:
P212121
Expression systems:
- Escherichia coli BL21(DE3)
- Escherichia coli
