1ok2

X-ray diffraction
2.5Å resolution

Decay accelerating factor (CD55): the structure of an intact human complement regulator.

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-139970 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Complement decay-accelerating factor Chains: A, B
Molecule details ›
Chains: A, B
Length: 254 amino acids
Theoretical weight: 28.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P08174 (Residues: 35-285; Coverage: 72%)
Gene names: CD55, CR, DAF
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: P1
Unit cell:
a: 47.58Å b: 55.62Å c: 61.53Å
α: 86.56° β: 84.44° γ: 64.22°
R-values:
R R work R free
0.229 not available not available
Expression system: Escherichia coli