› 1oqx

X-ray diffraction
2.6Å resolution

G-2 glycovariant of human IgG Fc bound to minimized version of Protein A called Z34C

Released:
DOI: 10.2210/pdb1oqx/pdb
PDB entry 1oqx coloured by chain, front view.
PDB entry 1oqx coloured by chain, side view.
PDB entry 1oqx coloured by chain, top view.
Source organisms:
Entry authors: Raju TS, Mulkerrin MG, Parker M, De Vos AM, Gazzano-Santoro H, Totpal K, Ultsch MH

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134866 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Immunoglobulin heavy constant gamma 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 212 amino acids
Theoretical weight: 23.98 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P01857 (Residues: 119-328; Coverage: 53%)
Gene name: IGHG1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Protein A Z34C Chains: C, D
Molecule details ›
Chains: C, D
Length: 34 amino acids
Theoretical weight: 4.19 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN, FUL
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN, FUC
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P21212
Unit cell:
a: 87.43Å b: 125.68Å c: 53.64Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.24 0.219 0.306
Expression systems:
  • Cricetulus griseus
  • Not provided

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