› 1oyx

X-ray diffraction
1.85Å resolution

CRYSTAL STRUCTURE OF 3-MBT REPEATS OF LETHAL (3) MALIGNANT BRAIN TUMOR (SELENO-MET) AT 1.85 ANGSTROM

Released:
DOI: 10.2210/pdb1oyx/pdb
PDB entry 1oyx coloured by chain, front view.
PDB entry 1oyx coloured by chain, side view.
PDB entry 1oyx coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Malignant brain tumor repeats: a three-leaved propeller architecture with ligand/peptide binding pockets.
Wang WK, Tereshko V, Boccuni P, MacGrogan D, Nimer SD, Patel DJ
Structure 11 775-89 (2003)
PMID: 12842041

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195226 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lethal(3)malignant brain tumor-like protein 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 331 amino acids
Theoretical weight: 38.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y468 (Residues: 265-595; Coverage: 39%)
Gene names: KIAA0681, L3MBT, L3MBTL, L3MBTL1
Sequence domains: mbt repeat
Structure domains: SH3 type barrels.

Ligands and Environments

2 bound ligands:
Ligand SO4 14 x SO4
Ligand MES 7 x MES
1 modified residue:
Ligand MSE 15 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-ID-B
Spacegroup: P32
Unit cell:
a: 105.656Å b: 105.656Å c: 90.369Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.209 0.207 0.238
Expression system: Escherichia coli

Quick links

Citations

10 review citations

How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers.
Taverna et al. (2007)
9 more

3 mentions without citation

Malignant brain tumor repeats: a three-leaved propeller architecture with ligand/peptide binding pockets.
Wang et al. (2003)
2 more