› 1p1t

Solution NMR

NMR Structure of the N-terminal RRM domain of Cleavage stimulation factor 64 KDa subunit

Released:
DOI: 10.2210/pdb1p1t/pdb
PDB entry 1p1t coloured by chain, ensemble of 20 models, front view.
PDB entry 1p1t coloured by chain, ensemble of 20 models, side view.
PDB entry 1p1t coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein.
Pérez Cañadillas JM, Varani G
EMBO J 22 2821-30 (2003)
PMID: 12773396

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152564 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cleavage stimulation factor subunit 2 Chain: A
Molecule details ›
Chain: A
Length: 104 amino acids
Theoretical weight: 11.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P33240 (Residues: 8-111; Coverage: 18%)
Gene name: CSTF2
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

13 review citations

RNA-binding proteins: modular design for efficient function.
Lunde et al. (2007)
12 more

11 mentions without citation

Delineating the structural blueprint of the pre-mRNA 3'-end processing machinery.
Xiang et al. (2014)
10 more