› 1p32

X-ray diffraction
2.25Å resolution

CRYSTAL STRUCTURE OF HUMAN P32, A DOUGHNUT-SHAPED ACIDIC MITOCHONDRIAL MATRIX PROTEIN

Released:
DOI: 10.2210/pdb1p32/pdb
PDB entry 1p32 coloured by chain, front view.
PDB entry 1p32 coloured by chain, side view.
PDB entry 1p32 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of human p32, a doughnut-shaped acidic mitochondrial matrix protein.
Jiang J, Zhang Y, Krainer AR, Xu RM
Proc Natl Acad Sci U S A 96 3572-7 (1999)
PMID: 10097078

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170441 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Complement component 1 Q subcomponent-binding protein, mitochondrial Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 209 amino acids
Theoretical weight: 23.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07021 (Residues: 74-282; Coverage: 74%)
Gene names: C1QBP, GC1QBP, HABP1, SF2P32
Sequence domains: Mitochondrial glycoprotein
Structure domains: Mitochondrial glycoprotein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P21
Unit cell:
a: 58.625Å b: 56.481Å c: 93.831Å
α: 90° β: 95.99° γ: 90°
R-values:
R R work R free
0.173 0.173 0.234
Expression system: Escherichia coli

Quick links

Citations

28 review citations

Mitochondria in innate immune responses.
West et al. (2011)
27 more

155 mentions without citation

Infections of people with complement deficiencies and patients who have undergone splenectomy.
Ram et al. (2010)
154 more