› 1pdr

X-ray diffraction
2.8Å resolution

CRYSTAL STRUCTURE OF THE THIRD PDZ DOMAIN FROM THE HUMAN HOMOLOG OF DISCS LARGE PROTEIN

Released:
DOI: 10.2210/pdb1pdr/pdb
PDB entry 1pdr coloured by chain, front view.
PDB entry 1pdr coloured by chain, side view.
PDB entry 1pdr coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of a PDZ domain.
Morais Cabral JH, Petosa C, Sutcliffe MJ, Raza S, Byron O, Poy F, Marfatia SM, Chishti AH, Liddington RC
Nature 382 649-52 (1996)
PMID: 8757139

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171457 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Disks large homolog 1 Chain: A
Molecule details ›
Chain: A
Length: 99 amino acids
Theoretical weight: 10.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12959 (Residues: 457-555; Coverage: 11%)
Gene name: DLG1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P6322
Unit cell:
a: 110.97Å b: 110.97Å c: 62.47Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.22 0.22 0.271
Expression system: Escherichia coli

Quick links

Citations

45 review citations

PDZ domains and the organization of supramolecular complexes.
Sheng et al. (2001)
44 more

7 mentions without citation

Specificity in PDZ-peptide interaction networks: Computational analysis and review.
Amacher et al. (2020)
6 more