› 1pex

X-ray diffraction
2.7Å resolution

COLLAGENASE-3 (MMP-13) C-TERMINAL HEMOPEXIN-LIKE DOMAIN

Released:
DOI: 10.2210/pdb1pex/pdb
PDB entry 1pex coloured by chain, front view.
PDB entry 1pex coloured by chain, side view.
PDB entry 1pex coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The helping hand of collagenase-3 (MMP-13): 2.7 A crystal structure of its C-terminal haemopexin-like domain.
Gomis-Rüth FX, Gohlke U, Betz M, Knäuper V, Murphy G, López-Otín C, Bode W
J Mol Biol 264 556-66 (1996)
PMID: 8969305

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155286 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Collagenase 3 Chain: A
Molecule details ›
Chain: A
Length: 207 amino acids
Theoretical weight: 24.18 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
UniProt:
  • Canonical: P45452 (Residues: 265-471; Coverage: 46%)
Gene name: MMP13
Sequence domains: Hemopexin
Structure domains: Hemopexin-like domain

Ligands and Environments

3 bound ligands:
Ligand SO4 1 x SO4
Ligand CL 2 x CL
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3221
Unit cell:
a: 52.94Å b: 52.94Å c: 144.02Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.195 not available
Expression system: Mus musculus

Quick links

Citations

19 review citations

Matrix metalloproteinases.
Nagase et al. (1999)
18 more

7 mentions without citation

A normalized root-mean-square distance for comparing protein three-dimensional structures.
Carugo et al. (2001)
6 more