Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140820 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Granulocyte colony-stimulating factor
Molecule details ›
Chains: A, C, E, G
Length: 175 amino acids
Theoretical weight: 18.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Granulocyte colony-stimulating factor
Structure domains: Growth Hormone; Chain: A;
Length: 175 amino acids
Theoretical weight: 18.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P09919 (Residues: 31-207; Coverage: 98%)
Sequence domains: Granulocyte colony-stimulating factor
Structure domains: Growth Hormone; Chain: A;
Granulocyte colony-stimulating factor receptor
Molecule details ›
Chains: B, D, F, H
Length: 215 amino acids
Theoretical weight: 24.46 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
Structure domains: Immunoglobulins
Length: 215 amino acids
Theoretical weight: 24.46 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P40223 (Residues: 120-334; Coverage: 27%)
Structure domains: Immunoglobulins
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
PHOTON FACTORY BEAMLINE BL-6B
Spacegroup:
P43212
Expression systems:
- Escherichia coli
- Spodoptera frugiperda
