› 1ppq

Solution NMR

NMR structure of 16th module of Immune Adherence Receptor, Cr1 (Cd35)

Released:
DOI: 10.2210/pdb1ppq/pdb
PDB entry 1ppq coloured by chain, ensemble of 20 models, front view.
PDB entry 1ppq coloured by chain, ensemble of 20 models, side view.
PDB entry 1ppq coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Backbone dynamics of complement control protein (CCP) modules reveals mobility in binding surfaces.
O'Leary JM, Bromek K, Black GM, Uhrinova S, Schmitz C, Wang X, Krych M, Atkinson JP, Uhrin D, Barlow PN
Protein Sci 13 1238-50 (2004)
PMID: 15096630

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148214 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Complement receptor type 1 Chain: A
Molecule details ›
Chain: A
Length: 68 amino acids
Theoretical weight: 7.31 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P17927 (Residues: 1002-1065; Coverage: 3%)
Gene names: C3BR, CR1
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Simulated annealing and molecular dynamics
Expression system: Komagataella pastoris

Quick links

Citations

3 review citations

Evolutionary aspects of hemoglobin scavengers.
Wicher et al. (2010)
2 more

4 mentions without citation

Structural biology of complement receptors.
Santos-López et al. (2023)
3 more