› 1psr

X-ray diffraction
1.05Å resolution

HUMAN PSORIASIN (S100A7)

Released:
DOI: 10.2210/pdb1psr/pdb
PDB entry 1psr coloured by chain, front view.
PDB entry 1psr coloured by chain, side view.
PDB entry 1psr coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
EF-hands at atomic resolution: the structure of human psoriasin (S100A7) solved by MAD phasing.
Brodersen DE, Etzerodt M, Madsen P, Celis JE, Thøgersen HC, Nyborg J, Kjeldgaard M
Structure 6 477-89 (1998)
PMID: 9562557

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151915 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein S100-A7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 100 amino acids
Theoretical weight: 11.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P31151 (Residues: 2-101; Coverage: 99%)
Gene names: PSOR1, S100A7, S100A7C
Sequence domains: S-100/ICaBP type calcium binding domain
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand HO 2 x HO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P212121
Unit cell:
a: 46.805Å b: 61.631Å c: 62.772Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.109 not available 0.141
Expression system: Escherichia coli BL21

Quick links

Citations

21 review citations

S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles.
Donato R. (2001)
20 more

14 mentions without citation

Zooming into the Dark Side of Human Annexin-S100 Complexes: Dynamic Alliance of Flexible Partners.
Weisz et al. (2020)
13 more