1q1s

X-ray diffraction
2.3Å resolution

Mouse Importin alpha- phosphorylated SV40 CN peptide complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-136538 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Large T antigen Chains: A, B
Molecule details ›
Chains: A, B
Length: 24 amino acids
Theoretical weight: 2.6 KDa
Source organism: Betapolyomavirus macacae
Expression system: Not provided
UniProt:
  • Canonical: P03070 (Residues: 110-133; Coverage: 3%)
Importin subunit alpha-1 Chain: C
Molecule details ›
Chain: C
Length: 466 amino acids
Theoretical weight: 50.46 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P52293 (Residues: 70-529; Coverage: 87%)
Gene names: Kpna2, Rch1
Sequence domains:
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P212121
Unit cell:
a: 78.827Å b: 89.746Å c: 99.707Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.198 0.221
Expression systems:
  • Not provided
  • Escherichia coli